13 August 2008

Mesothelioma and Peritoneal Mesothelioma

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Mesothelioma is a form of cancer that is almost always caused by previous exposure to asbestos. In this disease, malignant cells develop in the mesothelium, a protective lining that covers most of the body's internal organs. Its most common site is the pleura (outer lining of the lungs and chest cavity), but it may also occur in the peritoneum (the lining of the abdominal cavity) or the pericardium (a sac that surrounds the heart).

Most people who develop mesothelioma have worked on jobs where they inhaled asbestos particles, or they have been exposed to asbestos dust and fibre in other ways, such as by washing the clothes of a family member who worked with asbestos. Unlike lung cancer, there is no association between mesothelioma and smoking. Compensation via asbestos funds or lawsuits is an important issue in mesothelioma.

The symptoms of mesothelioma include shortness of breath due to pleural effusion (fluid between the lung and the chest wall) or chest wall pain, and general symptoms such as weight loss. The diagnosis can be made with chest X-rays and a CT scan, and confirmed with a biopsy (tissue sample) and microscopic examination. A thoracoscopy (inserting a tube with a camera into the chest) can be used to take biopsies. It allows the introduction of substances such as talc to obliterate the pleural space (called pleurodesis), which prevents more fluid from accumulating and pressing on the lung. Despite treatment with chemotherapy, radiation therapy or sometimes surgery, the disease carries a poor prognosis. Research about screening tests for the early detection of mesothelioma is ongoing.

Source: Wikipedia, the free encyclopedia


Peritoneal Mesothelioma Information

Peritoneal Mesothelioma is a type of cancer that affects the peritoneum of the human abdominal cavity. Hence, this medical condition is also called as abdominal mesothelioma.

But before seeing more about peritoneal mesothelioma, let us first take a look at the classifications and functions of the peritoneum membrane.

Peritoneum is classified into visceral and parietal peritoneum. The visceral peritoneum envelops the abdominal organs and forms the periphery of the intestinal tract. On the other hand, parietal peritoneum covers the abdominal cavity. The purpose
of these layers is to protect the internal organs and to secrete a lubricating fluid that eases the movement of internal organs in the abdominal cavity.

Causes of Peritoneal Mesothelioma

Even though not a definitive explanation, it is widely considered that asbestos is the main cause for peritoneal mesothelioma. According to medical experts, in two ways asbestos dust could reach the intestine lining one through involuntary ingestion during working long hours and days amid asbestos, and secondly, through the lungs while breathing and hence along the lymph nodes to the peritoneal cavity. Either way, it is injurious to the human body, and may invariably lead to this cancerous condition if exposed to for a longer period of time.

Symptoms of Peritoneal Mesothelioma

Peritoneal mesothelioma, like the other forms of mesothelioma, shows a very long latency period and it wont be until 20-30 years since the asbestos-exposure days before any typical symptoms becomes apparent. But by then it will be too late to check the disease or provide any constructive medication or treatment. Further, a delay in diagnosing the disease can happen due to the fact that most of the symptoms of mesothelioma is not-specific and may resemble that of some other common and less serious diseases. For example, the common mesothelioma symptoms include anemia, fever, weight loss, abdominal pain, and bowel obstruction, and it is highly likely that the doctor initially may consider other options than contemplating cancer.
Therefore, the patient telling the doctor about any previous asbestos exposure in the first one-to-one interaction itself is very crucial, and that helps the doctor to think of a possible mesothelioma threat even before considering other
possibilities.

Treatments

Once the disease has been diagnosed, the doctor recommends the treatments based on several factors such as the extent of the damage, age and medical history of the person and overall health. The traditional treatments for mesothelioma include surgery if the tumor has spread out and is beyond radiation-curable radiation therapy (external and internal radiation),and chemotherapy, which includes using a pill or needle to insert anti-carcinogen drugs into the body.

With the advancement in science and technology, newer treatment techniques have been introduced, and some of it is looking promising as well.

Intraoperative photodynamic therapy is one such newer method that uses special drugs and light to destroy cancer cells. This method is used to study the earlier phases of mesothelioma in the chest.

Further, Immunotherapy is a way of boosting the immunity of ones own body against the spread of cancer. Also, recently, researches have found that Gene Therapy is effective in correcting the faulty genes causing mesothelioma. But these two methods are still in the clinical trials and are yet to be implemented in hospitals.

Even though a wide range of treatments are available for mesothelioma, clinical experiences reveals that none of this alone is capable of checking the disease effectively.

Article Source: http://www.articlesnatch.com

About the Author:
Christian Louis. Webmaster of several sites around the internet. Copy and paste the below link into your browser to learn more about mesothelioma http://www.online-mesothelioma-information.com


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